Cancer Driver Genes: Methods and Protocols, ISBN-13: 978-1493989669

Cancer Driver Genes: Methods and Protocols, ISBN-13: 978-1493989669

[PDF eBook eTextbook]

• Series: Methods in Molecular Biology (Book 1907)
• 214 pages
• Publisher: Humana; 1st ed. 2019 edition (December 13, 2018)
• Author(s): Timothy K. Starr
• Language: English
• ISBN-10: 1493989669
• ISBN-13: 978-1493989669

This book presents protocols for identification of genetic drivers of cancer. Chapters guide readers through a brief history of cancer gene discovery, in silico approaches, in vitro approaches, and in vivo approaches using forward genetic screens in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Cancer Driver Genes: Methods and Protocols aims to provide protocols that will be used and adapted by cancer researchers to expand the knowledge base of molecular mechanisms contributing to initiation, progression, and metastasis of cancer.

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